SAM D21 Arm® Cortex®-M0+ Microcontrollers

Microchip Technology SAM D21 Arm® Cortex®-M0+ Microcontrollers (MCUs) are low-power MCUs that range from 32- to 64-pins with up to 256KB Flash and 32KB of SRAM. The Microchip Technology SAM D21 MCUs have a maximum 48MHz frequency and reach 2.46 CoreMark/MHz. The devices are designed for simple and intuitive migration with identical peripheral modules. Features include hex-compatible code, identical linear address map, and pin-compatible migration paths between all devices in the product series. All devices include intelligent and flexible peripherals, an Event System for inter-peripheral signaling, and support for capacitive touch buttons, slider, and wheel user interfaces.

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Description Datasheet Availability Pricing (USD) Filter the results in the table by unit price based on your quantity.
Qty. RoHS ECAD Model Series
Mounting Style
Package/Case
Core
Program Memory Size
Data Bus Width
ADC Resolution
Maximum Clock Frequency
Number of I/Os
Data RAM Size
Supply Voltage - Min
Supply Voltage - Max
Minimum Operating Temperature
Maximum Operating Temperature
Qualification
Packaging
Microchip Technology ARM Microcontrollers - MCU 32TQFP,85C TEMP, GREEN, 3.3V, 48MHZ, T&R
Datasheet
2,800In Stock
MouseReel Available
Min.: 1
Mult.: 1
: 2,000

SAMD21 SMD/SMT TQFP-32 ARM Cortex M0+ 64 kB 32 bit 12 bit 48 MHz 26 I/O 8 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 32QFN 125C, GREEN,1.6-3.6V,48MHz,T&R
Datasheet
5,356In Stock
MouseReel Available
Min.: 1
Mult.: 1
: 5,000

SAMD21 SMD/SMT QFN-32 ARM Cortex M0+ 64 kB 32 bit 12 bit 48 MHz 26 I/O 8 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 128KB 16KB32QFN GRN1.6-3.6V48MHz
Datasheet
795In Stock
Min.: 1
Mult.: 1

SAMD21 SMD/SMT QFN-32 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 26 I/O 16 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray

Microchip Technology ARM Microcontrollers - MCU CM0,TQFP32, 128kFlash,Trays,USB, I Temp
Datasheet
1,889In Stock
Min.: 1
Mult.: 1

SAMD21 SMD/SMT TQFP-32 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 26 I/O 16 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU CM0,QFN32, 128kFlash,Trays,USB, I Temp
Datasheet
801In Stock
Min.: 1
Mult.: 1

SAMD21 SMD/SMT VQFN-32 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 26 I/O 16 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 32QFN IND TEMP, GREEN,1.6-3.6V,48MHz
Datasheet
2,982In Stock
Min.: 1
Mult.: 1
: 5,000

SAMD21 SMD/SMT VQFN-32 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 26 I/O 16 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape
Microchip Technology ARM Microcontrollers - MCU CMO,QFN32,Ligthing,128KFlash,Trays, 105 C
Datasheet
880In Stock
Min.: 1
Mult.: 1

SAMD21 SMD/SMT VQFN-32 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 26 I/O 16 kB 1.62 V 3.63 V - 40 C + 105 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 32QFN 125C, GREEN,1.6-3.6V,48MHz
Datasheet
1,241In Stock
MouseReel Available
Min.: 1
Mult.: 1
: 5,000

SAMD21 SMD/SMT QFN-32 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 26 I/O 32 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 256KB 32QFN GRN 1.6-3.6V 48MHz
Datasheet
2,330In Stock
Min.: 1
Mult.: 1

SAMD21 SMD/SMT QFN-32 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 26 I/O 32 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 48QFN,85C TEMP, GREEN, 3.3V, 48MHZ, T&R
Datasheet
3,301In Stock
MouseReel Available
Min.: 1
Mult.: 1
: 4,000

SAMD21 SMD/SMT QFN-48 ARM Cortex M0+ 32 kB 32 bit 12 bit 48 MHz 38 I/O 4 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 128KB 16KB 48QFN GRN1.6-3.6V48MHz
Datasheet
3,348In Stock
MouseReel Available
Min.: 1
Mult.: 1
: 4,000

SAMD21 SMD/SMT QFN-48 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 38 I/O 16 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU CM0,TQFP48, 128kFlash,Trays,USB, I Temp
Datasheet
900In Stock
Min.: 1
Mult.: 1

SAMD21 SMD/SMT TQFP-48 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 38 I/O 16 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU CM0,TQFP48, 128kFlash,T&R,USB, I Temp
Datasheet
1,402In Stock
Min.: 1
Mult.: 1
: 2,500

SAMD21 SMD/SMT TQFP-48 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 38 I/O 16 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape
Microchip Technology ARM Microcontrollers - MCU 256KB 32KB 48TQFP GRN1.6-3.6V48MHz
Datasheet
2,953In Stock
Min.: 1
Mult.: 1

SAMD21 SMD/SMT TQFP-48 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 38 I/O 32 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 256KB 32KB 48TQFP GRN1.6-3.6V48MHz
Datasheet
2,106In Stock
5,000Expected 23/07/2026
MouseReel Available
Min.: 1
Mult.: 1
: 2,500

SAMD21 SMD/SMT TQFP-48 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 38 I/O 32 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 256KB 32KB 48QFN GRN1.6-3.6V48MHz
Datasheet
734In Stock
Min.: 1
Mult.: 1

SAMD21 SMD/SMT QFN-48 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 38 I/O 32 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 64TQFP,85C TEMP, GREEN, 3.3V, 48MHZ, T&R
Datasheet
4,984In Stock
MouseReel Available
Min.: 1
Mult.: 1
: 1,500

SAMD21 SMD/SMT TQFP-64 ARM Cortex M0+ 64 kB 32 bit 12 bit 48 MHz 52 I/O 8 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 128KB 16KB 64TQFP GRN1.6-3.6V48MHz
Datasheet
2,112In Stock
2,560Expected 22/06/2026
Min.: 1
Mult.: 1

SAMD21 SMD/SMT TQFP-64 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 52 I/O 16 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU CM0, TQFP 64 , 128KFlash, USB, Extended Temp 125C, T&R
Datasheet
1,581In Stock
MouseReel Available
Min.: 1
Mult.: 1
: 1,500

SAMD21 SMD/SMT TQFP-64 ARM Cortex M0+ 128 kB 32 bit 48 MHz 52 I/O 16 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 64TQFP 125C, GREEN,1.6-3.6V,48MHz
Datasheet
910In Stock
2,080Expected 20/07/2026
Min.: 1
Mult.: 1

SAMD21 SMD/SMT TQFP-64 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 52 I/O 32 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 64TQFP 125C, GREEN,1.6-3.6V,48MHz
Datasheet
919In Stock
MouseReel Available
Min.: 1
Mult.: 1
: 1,500

SAMD21 SMD/SMT TQFP-64 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 52 I/O 32 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 256KB 32KB 64TQFP GRN1.6-3.6V48MHz
Datasheet
2,652In Stock
1,440Expected 21/05/2026
Min.: 1
Mult.: 1

SAMD21 SMD/SMT TQFP-64 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 52 I/O 32 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 256KB 32KB 64TQFP GRN1.6-3.6V48MHz
Datasheet
2,060In Stock
MouseReel Available
Min.: 1
Mult.: 1
: 1,500

SAMD21 SMD/SMT TQFP-64 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 52 I/O 32 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 32QFN,85C TEMP, GREEN, 3.3V, 48MHZ
Datasheet
626In Stock
Min.: 1
Mult.: 1

SAMD21 SMD/SMT QFN-32 ARM Cortex M0+ 32 kB 32 bit 12 bit 48 MHz 26 I/O 4 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 32QFN 125C, GREEN,1.6-3.6V,48MHz
Datasheet
63In Stock
Min.: 1
Mult.: 1

SAMD21 SMD/SMT QFN-32 ARM Cortex M0+ 32 kB 32 bit 12 bit 48 MHz 26 I/O 4 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray